React4life MIVO®: Multi In Vitro Organ

Multi In Vitro Organ MIVO® device React4life is an Italian company founded to help researchers recreating a reliable human-like platform in the lab, where they can advance their assays towards more predictive and reproducible drugs/molecules tests. React4life has patented and fully industrialized MIVO®: Multi In Vitro Organ, an innovative microphysiological system that comes from over 15 years of academic research.

Activity Description

The Multi In Vitro Organ MIVO® device is a cell/tissue culture chamber that recapitulates the physiological fluid-dynamic conditions.

MIVO® device, assembled to a pumping system, provides a controlled and reproducible fluid flow in terms of direction, speed and induced shear stresses, enabling to mimic different physiological flows affecting the cells/tissue behaviour.

MIVO® can be used:

  • for enhancing tissues conditions and prolonging lifetime, 
  • for advanced drug testing assays on 2D cells monolayers/3D reconstructed tissues/biopsies, 
  • for discovering new therapeutic approaches, 
  • for basic research, without involving animal use.

React4life may:

  • provide organ on chip technologies for culturing a range of hepatocytes cell types for toxicity assays
  • provide organ on chip technologies for culturing 3D cells/tissue culture and/or co-cultures (multi-organ on chips) for toxicity assays
  • provide consulting and trainings course for the adoption of organ on chip technologies on the methods above


SaferWorldbyDesign integrates in silico and in vitro methods to develop standard and premium Integrated Approaches to Testing and Assessment (IATAs), including methods that support ingredient and formulation screening and testing, product design and the preparation of Regulatory Dossiers.


Edelweiss Connect GmbH is registered as a limited company with Handelsregisteramt of Kanton Basel-Stadt

Swiss ID (UID) number: CHE-114.414.615

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