Single Cell Transcriptome Analyses of HepaRG™ Cells using cellenONE Technology A comparison of spheroids vs 2D culture
SaferWorldbyDesign Webinars

Tuesday, 26 January 2021 - 16:00 CET

Cellenion will present its solutions for single-cell analyses of 3D cellular models. Cellenion has developed cellenONE, a unique system able to both isolate single-cell with high accuracy and dispense nanoliters of reagents allowing miniaturization of sample preparation for OMICs studies.  The emergence of single-cell analyses has revolutionized Biology most notably in the field of Oncology. Making single-cell analyses affordable is critical to the deployment of these methods to other research fields.

In this webinar, we will present results from a comparative transcriptomic study on HepaRG  cells grown in traditional 2D monolayer versus 3D spheroids. This study demonstrates the power of single-cell analyses and confirms that HepaRG  cells grown as 3D spheroids show a more hepatic phenotype as compared to cells cultured in a 2D monolayer.

Speaker:  Guilhem Tourniaire

Guilhem Tourniaire undertook a doctorate in Chemical Biology under the supervision of Professor Mark Bradley at the University of Edinburgh. After graduating, Guilhem worked as a scientist at Smart Holograms (Cambridge) and Altrika (Sheffield). In 2013, he returned to France to take up a new challenge as a business developer for SCIENION AG, this assignment led to significant market growth and the creation of Cellenion in 2016, a SCIENION subsidiary based in Lyon, specialized in the fields of single-cell isolation and bioprinting.


SaferWorldbyDesign integrates in silico and in vitro methods to develop standard and premium Integrated Approaches to Testing and Assessment (IATAs), including methods that support ingredient and formulation screening and testing, product design and the preparation of Regulatory Dossiers.


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