Integrated Approaches to solving Skin Safety Assessment problems

This virtual meeting will include a perspective facilitated by Barry Hardy and a guest panel on Skin Safety Assessment on the following topics, followed by a discussion session.

• Barry Hardy, CEO, Edelweiss Connect - Insights from our stakeholder industry perspective
• Christophe Chesne, CEO, Wepredic - Advances in formulation testing and assessment 
• Tomaž Mohorič, Computational Scientist, Edelweiss Connect - Use of machine learning methods in assessment  
• Michael Dourson & Bernard Gadagbui, TERA - Risk assessment perspectives

Skin safety is one of the most important goals of the consumer products industry. The cosmetics industry is a lead developer and end-user of new approach methods (NAMs) to replace previously used animal experiments. New human clinical evidence is only available when there is strong justification. The first step in product decision making should always be to consider using all currently available evidence from data and models including read-across. Additionally, new data from tiered testing approaches including NAMs applied to formulations can provide values for a safety assessment with increased confidence and reduced uncertainties.